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Nuclear and Energy Research Institute

Science and Technology to service life

Pilot production of bioterapêuticos in E. coli

Cultivation in genetically modified bacteria bioreactors.

The expression of human growth hormone (hGH) and of human prolactin (hPRL) was developed in 20 L bioreactor with working volume of 5 L. Studies of purification and physico-chemical and biological characterization were completed. In progress, the expression of hGH and hPRL antagonists.

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